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Growth Hormone Axis Research Moderate Evidence

GHRP-2

Second-generation GH-releasing hexapeptide. More potent GH pulse amplitude than GHRP-6 with less ghrelin-mediated appetite stimulation. Studied for GH deficiency, body composition, and anti-aging hormone optimization.

GHRPghrelin mimeticGH releasegrowth hormonesecretagogueGHS-R1apituitary
Half-life
~15–30 minutes; typically dosed 2–3x daily for sustained GH optimization
SKUs Available
2
Evidence Level
Moderate Evidence
Mechanism of Action

Synthetic ghrelin mimetic — binds GHS-R1a receptor on pituitary somatotrophs. Stimulates GH pulse without requiring CRH co-administration. Less gastric motility effect than GHRP-6. Moderate cortisol and prolactin co-stimulation. Synergistic with CJC-1295 or Mod-GRF(1-29).

Published Research Ranges & Study Context

Studies have administered: 100–300mcg per injection in research contexts; often combined with GHRH analogue

Important Research Framing These are ranges reported in published scientific studies. They are provided for educational context only and do not constitute dosing recommendations. Individual study parameters vary by design, population, and research objectives. This information is not medical advice.
Primary Research Findings

Robust GH pulsatile release demonstrated across multiple human studies. GH secretagogue clinical pharmacology well-characterized. Body composition improvements in GH-deficient subjects. IGF-1 elevation dose-dependent.

Moderate Evidence Phase 1/2 human trials available
Side Effects Observed in Research

Water retention; mild appetite increase (less than GHRP-6); transient cortisol and prolactin elevation; injection site reactions

Available Configurations (SKU Reference)
GH2-5 GH2-10
Compounds Studied in Combination

These compounds have been examined together in research literature. Combination use is not endorsed or recommended — this information is provided for research context only.

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Research Education Only: This compound profile is for educational purposes only. All information is sourced from published scientific literature. This is not medical advice. Not for human consumption. Consult qualified medical professionals for any health decisions. Regulatory status varies by jurisdiction.