Home Compound Library Growth Hormone Axis IGF-1 LR3
Growth Hormone Axis Research Preliminary

IGF-1 LR3

Long-acting IGF-1 analogue with arginine substitution and glutamate extension for reduced binding protein affinity. Higher bioavailability than native IGF-1.

igf-1growth factormuscleprotein synthesisanabolic
Half-life
~20–30 hours (vs 12–15 hours native IGF-1)
SKUs Available
2
Evidence Level
Preliminary
Mechanism of Action

Binds IGF-1 receptors. Promotes muscle protein synthesis via mTOR/PI3K/Akt signaling. LR3 modification reduces binding to IGFBPs, increasing free IGF-1 activity.

Published Research Ranges & Study Context

Studies have administered: 20–100mcg/day in research literature

Important Research Framing These are ranges reported in published scientific studies. They are provided for educational context only and do not constitute dosing recommendations. Individual study parameters vary by design, population, and research objectives. This information is not medical advice.
Primary Research Findings

Studies show superior anabolic effects vs. native IGF-1. Muscle hypertrophy and satellite cell activation demonstrated in animal models.

Preliminary Primarily preclinical + case reports
Side Effects Observed in Research

Hypoglycemia risk (mitogenic insulin-like activity), water retention, potential mitogenic effects with chronic high-dose use based on receptor activation profiles

Available Configurations (SKU Reference)
IG01 IG1
Compounds Studied in Combination

These compounds have been examined together in research literature. Combination use is not endorsed or recommended — this information is provided for research context only.

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Research Education Only: This compound profile is for educational purposes only. All information is sourced from published scientific literature. This is not medical advice. Not for human consumption. Consult qualified medical professionals for any health decisions. Regulatory status varies by jurisdiction.