Home Compound Library Immune & Anti-Aging Thymulin (Facteur Thymique Sérique)
Immune & Anti-Aging Research Preliminary

Thymulin (Facteur Thymique Sérique)

Zinc-dependent thymic nonapeptide — only thymic hormone requiring a cofactor for activity. Studied for immune restoration, anti-inflammatory effects, and has demonstrated analgesic properties in pain models. Declines with thymic involution.

thymusT-cellimmunezincanalgesicanti-inflammatorythymic hormone
Half-life
Short; pulsatile thymic secretion; zinc-dependent activation
SKUs Available
1
Evidence Level
Preliminary
Mechanism of Action

Zinc-thymulin complex (Zn-FTS) binds thymulin receptor on T-lymphocytes, promoting T-cell differentiation and maturation. Without zinc, biologically inactive. Anti-inflammatory: potent inhibitor of pro-inflammatory cytokines. Analgesic: central and peripheral mechanisms via opioid and GABA systems in rodent models.

Published Research Ranges & Study Context

Studies have administered: Research doses: 10ng–10mcg in animal models; human dosing not well established

Important Research Framing These are ranges reported in published scientific studies. They are provided for educational context only and do not constitute dosing recommendations. Individual study parameters vary by design, population, and research objectives. This information is not medical advice.
Primary Research Findings

Dardenne group (Pasteur Institute): immune restoration in aged and immunocompromised animals. Pain studies: gene therapy and intranasal delivery show potent analgesic effects equal to morphine without addiction potential in rodents. Human data limited but immunological activity confirmed.

Preliminary Primarily preclinical + case reports
Side Effects Observed in Research

Very limited human data; generally considered safe at physiological concentrations; zinc toxicity concerns at high doses only

Available Configurations (SKU Reference)
TML5
Compounds Studied in Combination

These compounds have been examined together in research literature. Combination use is not endorsed or recommended — this information is provided for research context only.

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Research Education Only: This compound profile is for educational purposes only. All information is sourced from published scientific literature. This is not medical advice. Not for human consumption. Consult qualified medical professionals for any health decisions. Regulatory status varies by jurisdiction.