Home Compound Library GLP-1 & Metabolic Retatrutide
GLP-1 & Metabolic Research High Evidence

Retatrutide

Triple agonist (GIP/GLP-1/Glucagon) under phase 2/3 investigation. Early trials show remarkable metabolic and weight-reduction signals.

triple agonistglp-1gipglucagonmetabolicobesity
Half-life
~6 days
SKUs Available
8
Evidence Level
High Evidence
Mechanism of Action

Simultaneous activation of GIP, GLP-1, and glucagon receptors — the first triagonist studied in human clinical trials.

Published Research Ranges & Study Context

Studies have administered: 1–12mg weekly in Phase 2 trials

Important Research Framing These are ranges reported in published scientific studies. They are provided for educational context only and do not constitute dosing recommendations. Individual study parameters vary by design, population, and research objectives. This information is not medical advice.
Primary Research Findings

Phase 2 trial (JAMA 2023) reported up to 24.2% weight reduction at 48 weeks — highest reported in a peptide trial to date.

High Evidence Multiple large human RCTs available
Side Effects Observed in Research

GI symptoms similar to GLP-1 class; dose-dependent nausea during uptitration

Available Configurations (SKU Reference)
RT5 RT10 RT15 RT20 RT30 RT40 RT50 RT60
Compounds Studied in Combination

These compounds have been examined together in research literature. Combination use is not endorsed or recommended — this information is provided for research context only.

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Research Education Only: This compound profile is for educational purposes only. All information is sourced from published scientific literature. This is not medical advice. Not for human consumption. Consult qualified medical professionals for any health decisions. Regulatory status varies by jurisdiction.