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Tissue Repair & Recovery Research Moderate Evidence

Thymosin Beta-4 (Full Length)

Full 43-amino-acid thymosin beta-4 molecule (parent compound; tb500 is the active fragment). Studied for cardiac repair, wound healing, hair follicle stimulation, and anti-inflammatory signaling. Different pharmacology from tb500 fragment.

thymosinactinwound healingcardiachair growthinflammationtissue repair
Half-life
Short plasma half-life; tissue-level biological effects sustained
SKUs Available
2
Evidence Level
Moderate Evidence
Mechanism of Action

Full-length TB4 sequesters actin monomers (G-actin) via LKKTET motif. Promotes cell migration, angiogenesis, and stem cell recruitment. Anti-inflammatory: downregulates NFκB, upregulates anti-inflammatory cytokines. Cardiac: activates epicardial progenitor cells for cardiac repair.

Published Research Ranges & Study Context

Studies have administered: 1.5–6mg per dose, varying frequency in tissue repair contexts

Important Research Framing These are ranges reported in published scientific studies. They are provided for educational context only and do not constitute dosing recommendations. Individual study parameters vary by design, population, and research objectives. This information is not medical advice.
Primary Research Findings

Cardiac repair: phase 2 (RegeneRx) for MI and stroke — mixed but promising signals. Wound healing: accelerated closure in multiple models. Hair: phase 2 trials for hair loss showed follicle stimulation. Dry eye: phase 3 completed with positive data.

Moderate Evidence Phase 1/2 human trials available
Side Effects Observed in Research

Generally well-tolerated; injection site reactions; long-term effects under study

Available Configurations (SKU Reference)
TB4-5 TB4-10
Compounds Studied in Combination

These compounds have been examined together in research literature. Combination use is not endorsed or recommended — this information is provided for research context only.

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Research Education Only: This compound profile is for educational purposes only. All information is sourced from published scientific literature. This is not medical advice. Not for human consumption. Consult qualified medical professionals for any health decisions. Regulatory status varies by jurisdiction.