Scientific Glossary

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Endotoxins are lipopolysaccharides (LPS) from gram-negative bacterial cell walls. They remain potent even after bacteria are killed. When injected, endotoxins can cause fever, inflammation, septic shock, and death at high levels. Research-grade injectables require endotoxin testing (typically LAL or recombinant factor C test). Acceptable limits for injectable compounds are typically <0.1-1 EU/mL depending on intended use. Endotoxin presence is a key quality control concern for research peptide supply.