Home › Compound Library › Body Composition › YK-11
Body Composition Research Emerging

YK-11

Steroidal SARM with unique dual mechanism: androgen receptor partial agonist AND myostatin inhibitor via follistatin induction. Studied for exceptional anabolic potential with potentially lower androgenic side effects than testosterone. Research compound only.

SARMmyostatinfollistatinandrogen receptoranabolicbody compositionresearch
Half-life
~6–10 hours estimated from steroidal pharmacology
SKUs Available
1
Evidence Level
Emerging
Mechanism of Action

Binds androgen receptor as partial agonist — selectively induces AR coactivator recruitment profile distinct from DHT. Simultaneously induces follistatin expression in muscle cells, suppressing myostatin signaling. Two distinct pro-anabolic mechanisms in one molecule. Steroidal backbone differs from non-steroidal SARMs.

Published Research Ranges & Study Context

Studies have administered: No established human research doses; animal and in vitro studies only; case reports of 5–10mg/day in experimental contexts

Important Research Framing These are ranges reported in published scientific studies. They are provided for educational context only and do not constitute dosing recommendations. Individual study parameters vary by design, population, and research objectives. This information is not medical advice.
Primary Research Findings

Kanno et al. (2011): original in vitro study showing myogenic differentiation enhancement. Follistatin induction confirmed in C2C12 cells. No completed human clinical trials. Animal pharmacology promising but human data lacking.

Emerging Early-stage research — limited human data
Side Effects Observed in Research

Insufficient human data; androgen receptor activity suggests testosterone suppression, cardiovascular lipid changes, hepatotoxicity risk from oral steroidal structure

Available Configurations (SKU Reference)
YK11
Compounds Studied in Combination

These compounds have been examined together in research literature. Combination use is not endorsed or recommended — this information is provided for research context only.

Want a Complete Research Monograph?

Our AI can generate a 2,000+ word deep-dive on YK-11 — including full clinical trial summaries, pharmacokinetics, and research frontiers.

Generate Deep Dive in Research Chat
Research Education Only: This compound profile is for educational purposes only. All information is sourced from published scientific literature. This is not medical advice. Not for human consumption. Consult qualified medical professionals for any health decisions. Regulatory status varies by jurisdiction.