Scientific Glossary

▾

NO is synthesized from arginine by three NOS isoforms: eNOS (endothelial — vasodilation), nNOS (neuronal — neurotransmission), iNOS (inducible — immune response). eNOS-derived NO relaxes vascular smooth muscle, reducing blood pressure and increasing blood flow. BPC-157 modulates NO synthesis — research shows it can both stimulate and normalize NO production depending on the research model context. This NO modulation may explain its observed effects on blood pressure and tissue perfusion in animal studies.