Compound Library

Evidence-based research summaries across 9 categories.

Research-Only Citation-Backed Evidence-Graded
13 compounds
Longevity & Mitochondrial Moderate
NAD+

Nicotinamide adenine dinucleotide — central coenzyme in cellular energy metabolism. Extensively studied for roles in aging, DNA repair, and mitochondrial function.

Longevity & Mitochondrial Preliminary
Epithalon

Synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from pineal gland research. Studied extensively in Soviet/Russian literature for telomere lengthening and longevity effects.

Longevity & Mitochondrial Emerging
MOTS-c

Mitochondrial-derived peptide encoded by the mitochondrial genome. Studied for roles in metabolic regulation, exercise performance, and longevity signaling.

Longevity & Mitochondrial Moderate
SS-31 / Elamipretide

Mitochondria-targeting peptide that selectively concentrates in the inner mitochondrial membrane. Studied for heart failure, kidney disease, and mitochondrial dysfunction.

Longevity & Mitochondrial Preliminary
Pinealon

Tripeptide (Glu-Asp-Arg) from pineal gland. Russian research program studied it for neuroprotective and longevity properties.

Longevity & Mitochondrial Moderate
Glutathione

Master antioxidant tripeptide (GSH). Studied for detoxification support, oxidative stress reduction, immune function, and skin health applications.

Longevity & Mitochondrial High Evidence
L-Carnitine

Amino acid derivative critical for fatty acid transport into mitochondria. Studied for cardiovascular health, exercise performance, and metabolic support.

Longevity & Mitochondrial Moderate
NMN (Nicotinamide Mononucleotide)

Direct NAD+ precursor studied for mitochondrial biogenesis, metabolic health, cardiovascular function, and longevity mechanisms. More bioavailable than NR for some tissues per recent comparative studies.

Longevity & Mitochondrial Moderate
Nicotinamide Riboside (NR)

NAD+ precursor vitamin B3 analogue. First orally bioavailable NAD+ booster with human clinical trial data. Studied for cardiovascular health, neuroprotection, metabolic function, and healthy aging.

Longevity & Mitochondrial Moderate
Rapamycin (Sirolimus)

mTOR inhibitor — among the most studied longevity compounds. Extends lifespan in every model organism tested including mice. Human longevity trials ongoing (PEARL trial, Participatory Evaluation of Aging with Rapamycin). Immune-suppression drug repurposed for aging research.

Longevity & Mitochondrial Preliminary
Fisetin

Flavonoid polyphenol (found in strawberries, apples) studied as a senolytic — selectively clears senescent "zombie" cells. Mayo Clinic clinical trials ongoing for frailty and age-related conditions.

Longevity & Mitochondrial Preliminary
Spermidine

Naturally occurring polyamine found in aged cheese, wheat germ, and mushrooms. Studied as an autophagy inducer with potential for cardiovascular protection, neuroprotection, and lifespan extension. Declines naturally with age.

Longevity & Mitochondrial Moderate
CoQ10 (Ubiquinol)

Mitochondrial electron transport chain cofactor. Studied for cardiovascular disease, statin-associated myopathy, heart failure, and mitochondrial dysfunction. Levels decline with age and statin use.

Research Reference Only: All compound information is for educational purposes from published literature. Not medical advice.